GLP-1

GLP-1 medications are prescription medications that mimic a naturally occurring hormone called glucagon-like peptide-1. They help regulate appetite, blood sugar, and digestion. Certain medications in this class are FDA-approved for chronic weight management in eligible patients and may help support long-term weight loss when combined with nutrition, physical activity, and ongoing medical care.

GLP-1 medications work by acting on pathways involved in appetite and fullness. They may help you feel satisfied sooner, reduce hunger, and decrease cravings for some foods. Certain medications also slow stomach emptying, which can help you feel full longer.

Results vary from person to person and depend on the medication, dose, treatment duration, lifestyle habits, and individual health factors.

Prescription weight-management medications may be appropriate for adults with a body mass index (BMI) of 30 or greater, or a BMI of 27 or greater with at least one weight-related medical condition, depending on the medication's approved indication.

Examples of weight-related conditions include high blood pressure, abnormal cholesterol, and type 2 diabetes.

Eligibility is determined through an individualized medical evaluation that considers your health history, current medications, treatment goals, and potential risks.

For eligible patients, GLP-1-based medications may help:

• Reduce hunger and appetite.

• Increase feelings of fullness.

• Support clinically meaningful weight loss.

• Improve blood sugar control with certain medications.

• Improve certain weight-related health conditions.

The extent of benefit varies by medication and individual. These medications work best as part of a comprehensive weight-management plan rather than as a stand-alone solution.

Some patients notice changes in appetite within the first few weeks. Meaningful weight changes generally develop over time as treatment is gradually adjusted and tolerated.

Many treatment plans begin with a lower dose and increase gradually according to the medication's prescribing instructions and the patient's response. Your provider will monitor your progress and determine whether adjustments are appropriate.

Weight loss varies depending on the medication, dose, duration of treatment, lifestyle changes, and individual health factors.

In clinical trials, adults without diabetes receiving semaglutide 2.4 mg lost an average of approximately 15% of their starting body weight over 68 weeks. Adults receiving tirzepatide at the studied maintenance doses lost an average of approximately 15% to 21% over 72 weeks, depending on the dose.

These are clinical trial averages, not guaranteed outcomes. Results in individual patients may be higher or lower, and results from different trials cannot be compared directly.

The most common side effects of GLP-1-based medications involve the digestive system and may include:

• Nausea.

• Vomiting.

• Diarrhea.

• Constipation.

• Abdominal discomfort.

• Bloating or indigestion.

Symptoms may be more noticeable when beginning treatment or increasing the dose. Your provider can help you manage side effects and determine whether treatment adjustments are needed.

Severe or persistent abdominal pain, especially if it radiates to the back, requires urgent medical evaluation. Persistent vomiting or signs of dehydration also warrant prompt medical attention.

GLP-1-based medications can be effective for eligible patients, but they have important risks and are not suitable for everyone.

Depending on the medication, risks may include pancreatitis, gallbladder problems, dehydration-related kidney injury, and severe gastrointestinal reactions. They may also increase the risk of low blood sugar when used with certain diabetes medications.

Semaglutide and tirzepatide products approved for weight management carry warnings concerning thyroid C-cell tumors observed in rodents. They should not be used by patients with a personal or family history of medullary thyroid carcinoma or by patients with multiple endocrine neoplasia syndrome type 2 (MEN2).

Your provider will review the medication-specific warnings, contraindications, and precautions before treatment.

The cost depends on the medication prescribed, dose, pharmacy, insurance coverage, and the services included in your treatment plan. Medication coverage and out-of-pocket expenses vary.

Contact F&P Aesthetics for information about consultation fees, available treatment options, and current pricing. We can discuss the costs associated with your individualized plan before treatment begins.